Drs. Belgin Dogan and Kenneth W. Simpson of Cornell University needed a color illustration that would highlight Adherent-invasive Escherichia coli (AIEC), and its interactions with the canine intestinal villous epithelium and Peyer’s patch dome epithelium when linked to dysbiosis, a focus of their research. Isolation of AIEC from intestines of humans with Crohn’s disease, dogs with granulomatous colitis, and mice with acute ileitis suggests that these bacteria share some pathoadaptive virulence factors that promote inflammation.
